@inproceedings{GamLamRig06-DTMIB-IW, author = { Giacomo Gamberoni and Evelina Lamma and Fabrizio Riguzzi and Sergio Storari and Chiara Scapoli}, title = {Marker Analysis with APRIORI-Based Algorithms}, booktitle = {Notes from the Workshop on Data and Text Mining for Integrative Biology of the 17th European Conference on Machine Learning ({ECML}'2006) and the 10th European Conference on Principles and Practice of Knowledge Discovery in Databases ({PKDD}'2006)}, address = {Berlin, \Germany}, month = sep, year = {2006}, editor = {Melanie Hilario and Claire N\'edellec}, pages = {61--66}, http = {http://www.ecmlpkdd2006.org/ws-dtib.pdf}, pdf = {http://ml.unife.it/wp-content/uploads/Papers/GamLamRig-DTMIB.pdf}, abstract = {In genetic studies, polygenic diseases are often analyzed searching for marker patterns that play a significant role in the susceptibility to the disease. In this paper we consider a dataset regarding periodontitis, that includes the analysis of nine genetic markers for 148 patients. We analyze these data by using two APRIORI-based algorithms: APRIORI-SD and APRIORI with filtering. The discovered rules (especially those found by APRIORI with filtering) confirmed the results published on periodontitis.} }
@article{LamMelNan06-TITB-IJ, author = {Evelina Lamma and Paola Mello and Annamaria Nanetti and Fabrizio Riguzzi and Sergio Storari and Gianfranco Valastro}, title = {Artificial Intelligence Techniques for Monitoring Dangerous Infections}, journal = {IEEE Transaction on Information Technology in Biomedicine}, year = {2006}, publisher = {IEEE Computer Society Press}, address = {Washington, DC, \USA}, volume = {10}, number = {1}, pages = {143-155}, month = jan, issn = {1089-7771}, doi = {10.1109/TITB.2005.855537}, pdf = {http://ml.unife.it/wp-content/uploads/Papers/LamMelNanRigStoVal-TITB06.pdf}, abstract = { The monitoring and detection of nosocomial infections is a very important problem arising in hospitals. A hospital-acquired or nosocomial infection is a disease that develops after the admission into the hospital and it is the consequence of a treatment, not necessarily a surgical one, performed by the medical staff. Nosocomial infections are dangerous because they are caused by bacteria which have dangerous (critical) resistance to antibiotics. This problem is very serious all over the world. In Italy, actually almost 5-8\% of the patients admitted into hospitals develop this kind of infection. In order to reduce this figure, policies for controlling infections should be adopted by medical practitioners. In order to support them in this complex task, we have developed a system, called MERCURIO, capable of managing different aspects of the problem. The objectives of this system are the validation of microbiological data and the creation of a real time epidemiological information system. The system is useful for laboratory physicians, because it supports them in the execution of the microbiological analyses; for clinicians, because it supports them in the definition of the prophylaxis, of the most suitable antibiotic therapy and in the monitoring of patients' infections, and for epidemiologists, because it allows them to identify outbreaks and to study infection dynamics. In order to achieve these objectives we have adopted expert system and data mining techniques. We have also integrated a statistical module that monitors the diffusion of nosocomial infections over time in the hospital and that strictly interacts with the knowledge based module. Data mining techniques have been used for improving the system knowledge base. The knowledge discovery process is not antithetic, but complementary to the one based on manual knowledge elicitation. In order to verify the reliability of the tasks performed by MERCURIO and the usefulness of the knowledge discovery approach, we performed a test based on a dataset of real infection events. In the validation task MERCURIO achieved an accuracy of 98.5\%, a sensitivity of 98.5\% and a specificity of 99\%. In the therapy suggestion task MERCURIO achieved very high Accuracy and Specificity as well. The executed test provided many insights to experts too (we discovered some of their mistakes). The knowledge discovery approach was very effective in validating part of MERCURIO knowledge base and also in extending it with new validation rules, confirmed by interviewed microbiologists and peculiar to the hospital laboratory under consideration.}, keywords = {Microbiology, Knowledge Based Systems, Decision Support Systems, Data Mining, Classification}, copyright = {IEEE} }
@incollection{LamRigSto06-BC, author = {Evelina Lamma AND Fabrizio Riguzzi AND Sergio Storari}, title = {Improving the K2 Algorithm Using Association Rule Parameters}, booktitle = {Modern Information Processing: From Theory to Applications}, editor = {Bernadette Bouchon-Meunier and Giulianella Coletti and Ronald Yager}, publisher = {Elsevier}, address = {Amsterdam, \TheNetherlands}, isbn = {0-444-52075-9}, year = {2006}, pages = {207--217}, doi = {10.1016/B978-044452075-3/50018-2}, pdf = {http://ml.unife.it/wp-content/uploads/Papers/LamRigSto-IPMUBK06.pdf}, url = {http://www.sciencedirect.com/science/article/pii/B9780444520753500182}, abstract = { A Bayesian network is an appropriate tool to work with the uncertainty that is typical of real-life applications. Bayesian network arcs represent statistical dependence between different variables and can be automatically elicited from database by Bayesian network learning algorithms such as K2. In the data mining field, association rules can also be interpreted as expressing statistical dependence relations. In this paper we present an extension of K2 called K2-rules that exploits a parameter normally defined in relation to association rules for learning Bayesian networks. We compare K2-rules with K2 and TPDA on the problems of learning four Bayesian networks. The experiments show that K2-rules improves both K2 and TPDA with respect to the quality of the learned network and K2 with respect to the execution time}, keywords = { Bayesian Networks, Machine Learning, Association Rules} }
@inproceedings{FlaMarRig06-RCRA06-NW, author = {Peter Flach and Valentina Maraldi and Fabrizio Riguzzi}, title = {Algorithms for Efficiently and Effectively Using Background Knowledge in Tertius}, pdf = {http://ml.unife.it/wp-content/uploads/Papers/FlaMarRig-RCRA06.pdf}, booktitle = {Incontro del Gruppo di Lavoro Rappresentazione della Conoscenza e Ragionamento Automatico ({RCRA}) dell'Associazione Italiana per l'Intelligenza Artificiale ({AI*IA}) dal titolo ``Analisi Sperimentale e Benchmark di Algoritmi per l'Intelligenza Artificiale'', 23 giugno 2006}, keywords = {Machine Learning, Inductive Logic Programming}, abstract = {\texttt{Tertius} is an Inductive Logic Programming system that performs confirmatory induction, i.e., it looks for the $n$ clauses that have the highest value of a confirmation evaluation function. In this setting, background knowledge is very useful because it can improve the reliability of the evaluation function, assigning minimal confirmation to clauses that are implied by the background knowledge and increasing the confirmation of the remaining clauses. We propose the algorithms \emph{Background1} and \emph{Background2} that look for clauses in the background that imply the clause under evaluation by \texttt{Tertius}. Both are based on a simplified implication test that is correct with respect to $\theta$-subsumption but not complete. The implication test is not complete because we want to keep the run time inside acceptable bounds. We compare \emph{Background1} with \emph{Background2} on two datasets. The results show that \emph{Background2} is more efficient than \emph{Background1}. Moreover, we also present the algorithm \emph{Preprocess} that infers new clauses from the background knowledge in order to exploit it as much as possible. The algorithm modifies the consequence finding algorithm proposed by Inoue by reducing its execution time while giving up completeness. }, editor = {Marco Gavanelli and Tony Mancini}, month = jun, year = {2006}, address = {Udine, \Italy} }
@inproceedings{LamMelRig06-RCRA06-NW, author = {Evelina Lamma and Paola Mello and Fabrizio Riguzzi}, title = {Exploiting Abduction for Learning from Incomplete Interpretations}, pdf = {http://ml.unife.it/wp-content/uploads/Papers/LamMelRig-RCRA06.pdf}, booktitle = {Incontro del Gruppo di Lavoro Rappresentazione della Conoscenza e Ragionamento Automatico ({RCRA}) dell'Associazione Italiana per l'Intelligenza Artificiale ({AI*IA}) dal titolo ``Analisi Sperimentale e Benchmark di Algoritmi per l'Intelligenza Artificiale'', 23 giugno 2006}, keywords = {Machine Learning, Inductive Logic Programming}, abstract = {In this paper we describe an approach for integrating abduction and induction in the ILP setting of learning from interpretations with the aim of solving the problem of incomplete information both in the background knowledge and in the interpretations. The approach is inspired by the techniques developed in the learning from entailment setting for performing induction from an incomplete background knowledge. Similarly to those techniques, we exploit an abductive proof procedure for completing the available background knowledge and input interpretations. The approach has been implemented in a system called AICL that is based on the ILP system ICL. Preliminary experiments have been performed on a toy domain where knowledge has been gradually removed. The experiments show that AICL has an accuracy that is superior to the one of ICL for levels of incompleteness between 5\% and 25\%. }, editor = {Marco Gavanelli and Tony Mancini}, month = jun, year = {2006}, address = {Udine, \Italy} }
@techreport{Rig06-TR, author = {Fabrizio Riguzzi}, title = {{ALLPAD}: Approximate Learning of Logic Programs with Annotated Disjunctions}, institution = {Dipartimento di Ingegneria, Universit\`{a} di Ferrara}, year = 2006, number = {CS-2006-01}, month = oct, pdf = {http://ml.unife.it/wp-content/uploads/Papers/ILP2006tr.pdf}, abstract = {Logic Programs with Annotated Disjunctions (LPADs) provide a simple and elegant framework for representing probabilistic knowledge in logic programming. In this paper I consider the problem of learning ground LPADs starting from a set of interpretations annotated with their probability. I present the system ALLPAD for solving this problem. ALLPAD modifies the previous system LLPAD in order to tackle real world learning problems more effectively. This is achieved by looking for an approximate solution rather than a perfect one. ALLPAD has been tested on the problem of classifying proteins according to their tertiary structures and the results compare favorably with most other approaches.}, keywords = {Probabilistic Inductive Logic Programming, Statistical Relational Learning} }
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